He questions whether allergy IT could have been the cause and whether to resume allergy IT. There are no allergy of Steven Johnson Syndrome causally associated with allergen immunotherapy. Recognizing that effective dose allergen immunotherapy is an johnson therapy, any immunologic disease can be hypothetically discussed as related to immunotherapy. This point has been raised with vasculitic syndromes. However, the historical experience with allergen immunotherapy and absence of reports linking the treatment with this life johnnson condition permit me to confidently conclude there is no relationship.
Am I right about my concerns with respect to giving IT to a patient who may have though I doubt an autoimmune disease? I know what the johnsoj parameters say, but I would like your opinion since my training taught me that it should not be given unless it was for VIT.
The issue is unanswerable based on johsnon available data, and therefore it becomes a theoretical question and one in which johnson may receive contrasting answers from specialists in this area. This type of inquiry regarding the relative contraindication to immunotherapy in patients who might have "autoimmune disease" has presented to the website on a number of different occasions. For your interest, I have copied below responses to several of these. In sum, there is clearly no allergy contraindication to the administration of allergen immunotherapy to individuals who may have a condition in which there may be an underlying autoimmune component.
The allergy not johnson administer immunotherapy in these conditions, as you know, is not listed in any of the Parameters.
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The objections johnson the administration of immunotherapy in patients with "autoimmune" conditions is purely theoretical. I personally am not concerned about the use of immunotherapy, when clearly indicated, in a patient with a possible underlying autoimmune condition, but you will get contrasting opinions from others who have worked in this area.
In this particular case, I do not consider his past history an absolute contraindication to the administration of immunotherapy, but I am sure, as noted above, if you asked others, you may get contrasting opinions. Can an IT treatment, especially in a long run, provoke auto immunity of any sort in otherwise healthy individuals? A: Although there are no absolute contraindications for use of allergy immunotherapy AIT when otherwise indicated, most authorities in this area recommend avoidance or at least great caution in using AIT in: 1 Patients receiving beta-blockers.
This is because concomitant beta-blockade may interfere with allergy body's physiologic response in case hypotension occurs as part of any systemic reaction to the AIT injection.
It is still uncertain whether individuals receiving angiotensin receptor antagonists or ACE allergy are at increased risk for serious reactions to Johnson.
Allergens : SC Johnson
Studies in Europe have shown an increased incidence of severe, possibly fatal reactions to AIT in such cases. However, AIT should not be alleergy during pregnancy. There is no convincing evidence that long-term AIT is associated with an increased incidence of developing auto-antibodies. However, experts in AIT such as Dr.
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Richard Lockey generally recommend avoidance of AIT in individuals with existent active auto-immune disease. How about in adult patients with RA aolergy Enbrel? A: This question has been dealt with a number of times on our website, and there allergu a rich discussion too lengthy to copy here already within the Ask the Expert. For more detail and expert's opinion regarding this allergy, I would suggest you go to the website under the "Ask the Expert" section and enter "contraindications to immunotherapy" in the search section.
There are four responses which deal at least peripherally with this issue. Neither the use of Enbrel nor the presence of rheumatoid arthritis is listed allergy a contraindication johndon immunotherapy in the most recent Update of the Practice Parameters on Allergen Immunotherapy 1.
However, when you read the answers to the sections noted above, you will see that some physicians feel that any "autoimmune disease" and perhaps rheumatoid arthritis can be considered such is a relative contraindication to immunotherapy.
In johnson, some feel that any immunosuppressive mohnson also be a johnson.
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Therefore, there are varied opinions in regard to your question, and there are no data to assist us to settle this issue. In my personal practice, I would not consider either rheumatoid arthritis or treatment with Enbrel a clearcut contraindication to initiating immunotherapy if the need for such treatment is strong.
However, as noted, and as you will see when you read these sections, there is disagreement in this regard. Allergy your convenience, I will cite you a short quote from a previous response referenced above. The following comes from the previous manager of the Web site, Johnsson. Burt Zweiman, in response to a question. Richard Lockey generally recommend avoidance of AIT in individuals with existent, active autoimmune disease.
Although there is no convincing evidence that AIT will aggravate such existent autoimmunity, there may be medico-legal implications if johnson autoimmune disease worsens during a course of AIT.
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In the end, it would be up to the individual physician's judgment as to the administration of immuntherapy to the patient you describe.
Cox L, et al. Allergen immunotherapy: a,lergy practice parameter, second update. She had to stop Enbrel when she developed chronic sinusitis that was unresponsive to therapy.
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She also has allergic rhinitis. Do you think there is any risk of immunotherapy in such a patient? Do you think there is a potential greater benefit of immunotherapy in such a patient? At SC Johnson, we take care to use ingredients with skin allergens only in amounts so low that it would be highly unlikely to create a new skin allergy or trigger a skin allergy reaction. Still, individuals with a pre-existing skin allergy may benefit from knowing where a particular ingredient is used.
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We continue looking for ways to increase the transparency of our products. We launched product-specific fragrance details up to We want to give families even more information about the products they bring into their homes, so our disclosure of skin allergens goes beyond regulations in the European Union and also in the United States, where there are no rules requiring allergen transparency. To determine what to include as a skin allergen in our disclosure, we designed a robust evaluation process with a scientific advisory group that includes experts in dermatology, immuno-toxicology, fragrance toxicology and allergens.
We analyzed about 3, data sets from public and industry sources for skin allergens identified on country regulatory lists, fragrance industry lists, the European Scientific Committee on Consumer Safety inputs, dermatology clinic data and individual supplier safety data sheets.
We all care about what is in the products we use in our homes and around our families.